Scientists who pioneered sequencing the genomes of cancer patients to find novel genetic changes at the root of the disease now have turned their attention to a laboratory workhorse – a mouse. By sequencing the genome of a mouse with cancer, researchers at Washington University School of Medicine in St. Louis have uncovered mutations that […]
While cancer statistics for the last 10 years make encouraging reading, more needs to be done globally to fight the killer disease. That is the view of cancer expert Dr. Mark Matfield of the Association for International Cancer Research (AICR) – a charity which annually awards millions of pounds to fund the best new research […]
Standard MRI scans have so far been unable to produce satisfactory images of nerve bundles. However, this is now possible by an MRI technique called Diffusion Tensor Imaging (DTI). Matthan Caan succeeded in improving the DTI method during his PhD research at Delft University of Technology, enabling him to produce more accurate images of the […]
A medicine widely used to treat attention-deficit/hyperactivity disorder (ADHD) also provides long-term relief from the attention and behavior changes that affect many childhood cancer survivors, according to a multicenter trial led by St. Jude Children’s Research Hospital investigators. The work appears in the September 13 online edition of the Journal of Clinical Oncology.
In Alzheimer’s disease, the problem is amyloid-β, a protein that accumulates in the brain and causes nerve cells to weaken and die. Drugs designed to eliminate plaques made of amyloid-β have a fatal problem: they need to enter the brain and remove the plaques without attacking healthy brain cells. A new breakthrough from the laboratory […]
Clinical trials using patients’ own immune cells to target tumors have yielded promising results. However, this approach usually works only if the patients also receive large doses of drugs designed to help immune cells multiply rapidly, and those drugs have life-threatening side effects. Now a team of MIT engineers has devised a way to deliver […]
Scientists have taken another important step toward understanding just how sticking needles into the body can ease pain. In a paper published online May 30 in Nature Neuroscience, a team at the University of Rochester Medical Center identifies the molecule adenosine as a central player in parlaying some of the effects of acupuncture in the […]
Three researchers who are recipients of a collaborative grant from the Samuel Waxman Cancer Research Foundation have developed a new type of drug designed to kill non-Hodgkin lymphoma tumor cells. The breakthrough could lead to potential non-toxic therapies for cancer patients. The Foundation-funded investigators include Ari Melnick, M.D., of Weill Cornell Medical College, Alexander MacKerell, […]
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