Early detection is key to more effective treatment for Alzheimer’s disease and other forms of cognitive impairment, and new research shows that a test developed at the University of Tennessee is more than 95 percent effective in detecting cognitive abnormalities associated with these diseases. The test, called CST – for computerized self test – was […]
Researchers at NYU School of Medicine have found that elevated cerebrospinal fluid levels of phosphorylated tau231 (P-tau231), a damaged tau protein found in patients with Alzheimer’s disease, may be an early diagnostic biomarker for Alzheimer’s disease in healthy adults. The study, published this month online by Neurobiology of Aging, shows that high levels of P-tau231 […]
Huntington’s disease (HD) is a cruel, hereditary condition that leads to severe physical and mental deterioration, psychiatric problems and eventually, death. Currently, there are no treatments to slow down or stop it. HD sufferers are born with the disease although they do not show symptoms until late in life. In a new study published in […]
Examining brain tissue from over 500 individuals in 11 countries, researchers from the University of Pennsylvania School of Medicine and the Children’s Hospital of Philadelphia, and colleagues found a new risk factor for the second-most-common cause of early-onset dementia after Alzheimer’s disease. “Using a genome-wide scan for genetic variation in post-mortem brain tissue, we were […]
For the first time, researchers from the University of Pennsylvania School of Medicine have found that three different degenerative brain disorders are linked by a toxic form of the same protein. The protein, called Elk-1, was found in clumps of misshaped proteins that are the hallmarks of Parkinson’s disease, Alzheimer’s disease, and Huntington’s disease. (continue […]
Cognitively stimulating activities are beneficial, but evidence suggests mental exercises help some more than others. If you don’t have a college degree, you’re at greater risk of developing memory problems or even Alzheimer’s. Education plays a key role in lifelong memory performance and risk for dementia, and it’s well documented that those with a college […]
A scientific group led by the Translational Genomics Research Institute (TGen) have identified three kinases, or proteins, that dismantle connections within brain cells, which may lead to memory loss associated with Alzheimer’s disease. These findings, the results of a multi-year TGen study, are published in this month’s edition of BMC Genomics in a paper titled: […]
Moderate physical activity performed in midlife or later appears to be associated with a reduced risk of mild cognitive impairment, whereas a six-month high-intensity aerobic exercise program may improve cognitive function in individuals who already have the condition, according to two reports in the January issue of Archives of Neurology, one of the JAMA/Archives journals.
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