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Fluorescent labeling of CalDAG-GEFI (red) and Htt (green) shows abundant expression of CalDAG-GEFI in the striatum of control mice (left panel) but severely down-regulated expression in striatal neurons of the Huntington's disease model mice (right panel). Aggregated Htt, a hallmark of Huntington's disease, is apparent in the neurons of mutant mice (green particles, right panel). Image courtesy Jill Crittenden/MIT

MIT Neuroscientists Unveil Molecular Pathway Involved With Huntington’s Disease

MIT researchers have discovered new molecular changes in the brains of individuals with Huntington’s disease, a genetic disorder that leads to neuronal loss accompanied by unwanted movements, psychiatric symptoms, and eventual death. By studying brains of human patients, as well as mouse and rat models, they have uncovered a protective response that may eventually lead […]

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Elk-1 Plague

Penn Study Finds That Three Brain Diseases Are Linked By A Toxic Form Of The Same Neural Protein

For the first time, researchers from the University of Pennsylvania School of Medicine have found that three different degenerative brain disorders are linked by a toxic form of the same protein. The protein, called Elk-1, was found in clumps of misshaped proteins that are the hallmarks of Parkinson’s disease, Alzheimer’s disease, and Huntington’s disease. (continue […]

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Source: Heidelberg University Hospital.

Deep Brain Stimulation Successful For Treatment Of A Severely Depressive Patient (World’s First Operation)

Neurosurgeons from University Hospital Heidelberg performed the world’s first operation on the ‘habenula’ to treat depression with cooperation from psychiatrists at the Central Institute of Mental Health in Mannheim. The team of neurosurgeons and psychiatrists have for the first time successfully treated a patient suffering from severe depression by stimulating the habenula, a tiny nerve […]

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Deep Brain Stimulation

An Overview Of Brain Stimulation Therapies

Brain stimulation therapies have received increased attention as of late. These treatments involve activating or touching the brain directly with electricity, magnets, or implants to treat depression and other disorders. One type of brain stimulation, Cranial Electrotherapy Stimulation (CES), was previously detailed in “What is CES?” Part 1 and Part 2. BMED Report even created […]

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The Scientist Research News Update 8-15-09

A brief but nonetheless interesting update for the 8-15-09 edition of The Scientist Research News Update. Check out the incredible report of how regenerative medicine induced a spinal cord to regrow sensory axons to their target destination, a new director for the National Institutes of Health (NIH), gender differences in HIV/AIDS progression, the Avian flu […]

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