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Physicians May Have Difficulty Recognizing Depression In The Elderly

an elderly womenDepression in the elderly is frequently unrecognized by physicians. Studies that examined the unassisted clinical ability of general practitioners to identify depression were divided into those of older adults, younger adults, and mixed populations. The results are published in Journal of Psychotherapy and Psychosomatics.

Data were extracted by 3 reviewers independently and pooled using a Bayesian meta-analysis. 31 valid studies that examined both sensitivity and specificity (or rule-in and rule-out accuracy) were identified, involving 52,513 individuals. Twelve studies recruited older individuals, 12 recruited younger adults and 7 recruited both younger and older adults (mixed populations).

In the most robust studies the point prevalence of depression in late life was 13.2% (95% CI = 7.9–19.6). GPs were able to correctly identify 47.3% of the late-life depressions and 78.6% of the non-cases (71.0% overall accuracy).

In younger adults GPs were able to identify 39.7% of the mid-life depressions and 85.1% of the non-depressed (77.8% overall accuracy). In mixed aged groups GPs were able to correctly identify 46.6% of the depressed individuals and 86.2% of the non-depressed (79.6% overall accuracy). The overall fraction correctly identified was significantly lower in older compared with younger adults. Correcting for differences in prevalence showed a statistically lower rule-in performance for older compared with younger adults.

There was no difference in ability to identify non-depressed (healthy) individuals by age. In clinical practice GPs appear to be less successful in identifying depression in older people than in younger adults, however there have been few head-to-head studies stratified by age from one centre.

Material adapted from Journal of Psychotherapy and Psychosomatics.

Reference
Mitchell, A.J. ; Rao, S. ; Vaze, A. Do Primary Care Physicians Have Particular Difficulty Identifying Late-Life Depression? A Meta-Analysis Stratified by Age. Psychother Psychosom 2010; 79:285-294.

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