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The coming weeks mark the return to school for many of our youngest citizens. Sadly the satisfaction of making new friends and obtaining good test scores may be overshadowed by the prospect of substance abuse for some school-aged adolescents. The previous decade has witnessed a two-fold increase in both alcohol consumption and intoxication by adolescents age 12 to 17 [1,2]. In an effort to combat these startling findings, researchers at King’s College London’s Institute of Psychiatry describe a successful personality-based intervention for substance abuse delivered by teachers.

Circadian rhythmicity is regulated by circadian clock genes, and animal studies have shown that chronic drinking can alter expressions in these genes. A new study has found that significantly lower levels of messenger ribonucleic acid (mRNA) – a molecule of RNA that helps to manufacture proteins – in circadian clock genes in alcohol-dependent (AD) patients support a relationship between circadian clock gene dysregulation and drinking in humans.

Blocking thoughts of cigarettes helps reduce smokers’ intake at first, but means they smoke more than usual when they stop suppressing, according to new research published in Psychological Science, a journal of the Association for Psychological Science. The study was carried out by researchers at St. George’s, University of London and the University of Hertfordshire.

A new study shows the impact of alcohol intoxication on reasoning and problem-solving abilities and may explain why some people feel they have recovered enough to drive after drinking. The research, led by Peter J. Snyder, PhD, vice president of research for Lifespan, is the first to explore how these cognitive abilities are impacted during both rising and declining blood alcohol concentrations, at matched blood alcohol level concentrations, and how self-evaluation of recovery differs from actual recovery from impairment.

If you want to know how people become addicted and why they keep using drugs, ask the people who are addicted. Thirty-one of 75 patients hospitalized for opioid detoxification told University at Buffalo physicians they first got hooked on drugs legitimately prescribed for pain. Another 24 began with a friend’s left-over prescription pills or pilfered from a parent’s medicine cabinet. The remaining 20 patients said they got hooked on street drugs. Results of the study appear in the current issue of Journal of Addiction Medicine.

Yale researchers have discovered how a novel anti-depressant can take effect in hours, rather than the weeks or months usually required for most drugs currently on the market. The findings, described in the August 20 issue of the journal Science, should speed development of a safe and easy-to-administer form of the anti-depressant ketamine, which has already proven remarkably effective in treating severely depressed patients.

A new study focused on anxiety and brain activity pinpoints the brain regions that are relevant to developing childhood anxiety. Specifically, Kalin and colleagues demonstrated that increased brain activity in the amygdala and anterior hippocampus could predict anxious temperament in young primates. The findings, published in the August 12th edition of the journal Nature, may lead to new strategies for early detection and treatment of at-risk children. Check the end of this report for a link to a video interview with the lead researcher.

Youth exposure to alcohol advertising in magazines declined by 48 percent between 2001 and 2008, according to a new study by the Center on Alcohol Marketing and Youth (CAMY) at the Johns Hopkins Bloomberg School of Public Health. Although 325 alcohol brands advertised in magazines in 2008, just 16 brands accounted for half of the advertising placed in publications more likely to be seen per capita by youth than by adults. Leading the list were Patron Silver Tequila, Absolut Vodka, Kahlua Liqueurs, Ketel One Vodka, and Jim Beam Bourbon Whiskey.

Adjusting the alcohol tax in Florida to account for inflation since 1983 would prevent 600 to 800 deaths each year in that state from diseases caused by chronic heavy alcohol use, according to a new study from the University of Florida. The Florida legislature last increased alcohol taxes in 1983. The research is published in the journal Alcoholism: Clinical and Experimental Research (ACER).

Cravings are the triggers that often lead to relapse in a host of addictions, which carry a staggering economic and social cost. Cigarette smoking alone is responsible for over 400,000 deaths per year in the U.S. (more than all illicit drugs and alcohol combined). Standard therapeutic techniques decrease cravings of cigarette smokers by regulating activity in two separate but related areas of the brain, a new study led by a Yale University researcher shows.
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