The closure of Pfizer’s Sandwich Lab is part of a long-term decline in drug development, a trend that has been affecting all major UK pharmaceutical multinationals. Big pharmaceutical companies have been downsizing, outsourcing, and merging in an attempts to find an innovation strategy that will keep their pipelines filled with new, potentially profitable products. This declining trend is blamed on a failure of innovative drive in the industry, failure of the UK to support basic research, failure of venture capital to invest in early stage research, or failure of the Health Service to provide smart procurement.
Tag Archives | Pharmacotherapy
This study published in the last 2010 issue of Psychotherapy and Psychosomatics suggests that therapist and patient ratings of therapeutic alliance predict therapeutic progress. This relation may be moderated by client characteristics, including ‘personality pathology comorbidity’ (i.e., the presence of multiple diagnoses), marital status, occupational status, and the atypical character of the major depressive episode.
The National Institute for Mental Health (NIMH) announced the release of “Social Phobia (Social Anxiety Disorder): Always Embarrassed” in their continuing series of free e-booklets that demystify common psychological disorders. Included in this review is a link to download this 6-page, full color e-booklet in PDF format.
Depression is expected to constitute the second largest source of global burden of disease after heart disease by the year 2020. The consequences for society and individuals are lowered quality of life, social isolation, decreased intellectual capacity as well as an inability to carry out activities of daily living. Additional consequences are significantly affected health levels, an increased need for institutionalized care along with an increased risk of suicide.
Among patients with depression, the presence of many aspects of illness which may be associated with bipolar disorder does not appear to be associated with treatment resistance – evidence against the common hypothesis that some cases of difficult-to-treat depression are actually unrecognized bipolar disorder. However, many patients with depression also report psychotic-like symptoms, such as hearing voices or believing they are being spied on or plotted against, and those who do are less likely to respond to treatment.
The enactment of the Patient Protection and Affordable Care Act of 2010 expands Medicare benefits to scores of previously uninsured individuals including many of our nation’s children. While access to treatment is laudable, the quality of such treatment is the subject of an article in the December issue of the Journal of the American Academy of Child and Adolescent Psychiatry.
The rate of depression treatment increased between 1998 and 2007 but at a slower rate than during the previous decade, and the percentage of patients treated with psychotherapy continued to decline, according to a report in the December issue of Archives of General Psychiatry, one of the JAMA/Archives journals.
In a recently published article in the journal, Applied Psychophysiology and Biofeedback, researchers report that neurofeedback, a form of biofeedback, significantly improves symptoms of fibromyalgia syndrome (FMS). The authors devised a well thought out study that included a total of 36 patients who experienced FMS. Patient were randomly assigned to 1 of 2 groups: 18 in a neurofeedback group and 18 in an Escitalopram (i.e., Lexipro) group.