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A hormone derived from visceral fat called adiponectin may play a role as a risk factor for development of all-cause dementia and Alzheimer disease (AD) in women, according to a study published Online First by the Archives of Neurology, one of the JAMA/Archives journals. The study was completed by Thomas M. van Himbergen, Ph.D., from the Lipid Metabolism Laboratory, Human Nutrition Research Center on Aging, Tufts University, Boston, and colleagues.

Obesity is associated with worse outcomes overall in early-stage breast cancer, researchers reported at the 2011 CTRC-AACR San Antonio Breast Cancer Symposium, held Dec. 6-10, 2011. Obesity was linked to shorter time to recurrence (TTR), disease-free survival (DFS) and overall survival (OS). The exception was treatment with endocrine therapy (mainly tamoxifen), in which obesity was associated with a protective effect.

Having diabetes or being obese after age 60 significantly increases the risk for developing breast cancer, a Swedish study has revealed. Data also showed that high blood lipids were less common in patients when diagnosed with breast cancer, while low blood lipids were associated with an increased risk. Researchers of the study also looked at overall cancer incidence and discovered that use of one diabetes drug was associated with a lower rate of any cancer, while another was associated with an increased risk.

A new analysis of national survey data finds that less than one-quarter of parents of overweight children recall ever being told by a doctor or other health care provider that their children were overweight. And although that percentage has increased over the last 10 years, more improvement is needed, said Eliana M. Perrin, MD, MPH, associate professor in the University of North Carolina at Chapel Hill School of Medicine, pediatrician at North Carolina Children’s Hospital, and lead author of the study.

A recent study of obese and non-obese children found that low vitamin D levels are significantly more prevalent in obese children and are associated with risk factors for type 2 diabetes. This study was accepted for publication in The Endocrine Society’s Journal of Clinical Endocrinology & Metabolism (JCEM).

A recent study of obese volunteers participating in a 12-week dietary weight-loss program found that successful weight losers had significantly higher resting nerve activity compared to weight-loss resistant individuals. The study was accepted for publication in The Endocrine Society’s Journal of Clinical Endocrinology & Metabolism (JCEM).

A healthy diet and the right amount of exercise are key players in treating and preventing obesity but we still know little about the relationship both factors have with each other. A new study now reveals that an increase in physical activity is linked to an improvement in diet quality. Many questions arise when trying to lose weight. Would it be better to start on a diet and then do exercise, or the other way around? And how much does one compensate the other?

A survey of more than 33,000 Italian high school students reveals that both underweight and overweight teens consume 20 to 40% more illegal drugs than their normal-weight peers. The work, led by Sabrina Molinaro and Francesca Denoth of the Italian National Research Council, is reported in the Nov. 16 issue of the online journal PLoS ONE. Check the end of this report for a link to download the full-text article.