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Fragile X And Down Syndromes Share Signalling Pathway For Intellectual Disability

Intellectual disability due to Fragile X and Down syndromes involves similar molecular pathways report researchers in The EMBO Journal. The two disorders share disturbances in the molecular events that regulate the way nerve cells develop dendritic spines, the small extensions found on the surface of nerve cells that are crucial for communication in the brain.

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Researchers Discover An Important New Piece To The Autism Puzzle

Most cases of autism are not caused by a single genetic mutation. However, several disorders with autism-like symptoms, including the rare Fragile X syndrome, can be traced to a specific mutation. Several years ago, MIT neuroscientist Mark Bear discovered that this mutation leads to overproduction of proteins found in brain synapses — the connections between […]

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New ADHD Gene Study Points To Defects In Brain Signaling Pathways

Pediatric researchers analyzing genetic influences in attention-deficit/hyperactivity disorder (ADHD) have found alterations in specific genes involved in important brain signaling pathways. The study raises the possibility that drugs acting on those pathways might offer a new treatment option for patients with ADHD who have those gene variants – potentially, half a million U.S. children.

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Depression And Anxiety Are Triggered By Combination Of Environmental, Psychological, And Genetic Factors

roblems like anxiety and depression are caused by psychological and environmental factors, and are known to be influenced by genetic proclivities. However, it is still not clear how each factor affects the brain’s functions to induce anxious and depressive symptoms. To shed light on these interactions, a team from the Centre Émotion-Remédiation et Réalité Virtuelle […]

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