A Developmental Gene-Environment Interactions Model For Psychosis

genetic manipulation

The incidence of psychotic disorders varies greatly across places and demographic groups, as do symptoms, course, and treatment response across individuals. High rates of schizophrenia in large cities, and among immigrants, cannabis users, and traumatized individuals reflect the causal influence of environmental exposures. This, in combination with progress in the area of molecular genetics, has generated interest in more complicated models of schizophrenia aetiology that explicitly posit gene-environment interactions.

Scientists Measure Gene Mutation Rate In Autism And Schizophrenia

On August 27, 2010, in Disease | Disorders, by Christopher Fisher, PhD
illustration of a genetic mutation

An international study led by University of Montreal scientists suggests family history may not be a good predictor of the presence of mutations predisposing to autism or schizophrenia. The findings show how new or de novo gene mutations – alterations of the cell’s DNA – play a role in these devastating conditions. Published in the American Journal of Human Genetics, this study has implications for disease prevalence and severity.

Physical Confirmation Of Neocortical Over-Connectivity In Autism Disorder

MRI of the human brain

There is still much that is unknown about autism spectrum disorders, but a University of Nevada, Reno psychologist has added to the body of knowledge that researchers around the world are compiling to try to demystify, prevent, and treat the mysterious condition. This research was published recently in the journal, Brain Research.

EEG Study Finds A Link Between Autism And Multisensory Integration

On August 19, 2010, in Autism, Highly Accessed, QEEG, by Christopher Fisher, PhD
research participant receiving an EEG

A new study by researchers at Albert Einstein College of Medicine of Yeshiva University has provided concrete evidence that children with autism spectrum disorders (ASD) process sensory information such as sound, touch, and vision differently than typically developing children. The results appear in the August 17 online issue of Autism Research. Included in this report is a video interview with the lead researcher who explains these results.

Disturbances In Certain Genes Play A Role In Autism

On August 16, 2010, in Disease | Disorders, by Christopher Fisher, PhD
DNA strand

Together with colleagues from an international research group, autism researcher Christopher Gillberg of the University of Gothenburg, Sweden, and member of the Autism Genome Project (AGP) research group, has found in a new study that autism can be partially explained by abnormalities in certain genes. The group’s results could, in the long run, pave the way for more appropriate treatments for autism. The results will be published in the journal, Nature.

Adult Autism Diagnosis By Brain Scan

MRI image of the brain

Scientists from the Institute of Psychiatry (IoP) at King’s College London have developed a pioneering new method of diagnosing autism in adults. For the first time, a quick brain scan that takes just 15 minutes can identify adults with autism with over 90 per cent accuracy. The method could lead to the screening for autism spectrum disorders in children in the future. The paper, ‘Describing the brain in autism in five dimensions – MRI-assisted diagnosis using a multi-parameter classification approach,’ is published in the Journal of Neuroscience today.

Children With Autism Do Not Benefit From Antidepressant Medication

anti-depressant-pills

Antidepressants commonly prescribed to people with autistic spectrum disorders cannot be recommended based on current evidence, a new study by Cochrane Researchers concludes. Despite some evidence of benefits in adults diagnosed with autism, they say there is no evidence for any benefits associated with selective serotonin reuptake inhibitors (SSRIs) in children, who may suffer serious adverse effects as a result of taking the drugs.

The Heavy Toll Of Autism On Marriages

Married couple holding hands with wedding rings showing

The parents of grown children with autism are more likely to divorce than couples with typically developing children, according to new data from a large longitudinal study of families of adolescents and adults with autism. The study, published in the August issue of the Journal of Family Psychology by researchers from the University of Wisconsin-Madison’s Waisman Center, paints a new picture of the prospects of long-term marital success for parents raising a child with autism.

Many Children With Sleep Disturbances Receive Medication

Picture of Judith Owens, MD

A new survey of child psychiatrists indicates that insomnia is a major problem among children in mental health treatment and at least a quarter of these patients are given sleep medication. The results of the survey, conducted by Judith Owens, MD, a sleep expert with Hasbro Children’s Hospital, and colleagues, suggests that management of insomnia in this population is a common practice, although the clinical approach varies widely. The study is published in the August 2010 edition of Sleep Medicine.

A New Speech Analysis Technology Reveals That Autism Has A Unique Vocal Signature

On July 20, 2010, in Disease | Disorders, by Christopher Fisher, PhD
young girl at the playground

The LENA™ (Language Environment Analysis) system automatically labeled infant and child vocalizations from recordings and thereafter an automatic acoustic analysis designed by the researchers showed that pre-verbal vocalizations of very young children with autism are distinctly different from those of typically developing children with 86 percent accuracy. The system also differentiated typically developing children and children with autism from children with language delay based on the automated vocal analysis.

Mothers Of Children With Autism Pay The Price In The Workplace

Female Thinking

Mothers of children with autism see their careers disproportionally affected as they confront greater demands on their time, inflexible workplaces and increased medical costs, according to a new study by researchers at Washington State University Vancouver. The paper will be published in the peer-reviewed Social Science Journal.

Large Study Helps Clarify The Genetics Of Autism

On July 1, 2010, in Autism, by Christopher Fisher, PhD
DNA

A large international consortium of researchers, including scientists at the University of North Carolina at Chapel Hill, have announced new discoveries that could help clarify the genetics of autism. Their findings published online June 9th in the journal Nature, support an emerging consensus among scientists that autism is caused by many “rare variants” or genetic [...]

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