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Depression may have more far-reaching consequences than previously believed. Recent data suggests that individuals who suffer from a mood disorder could be twice as likely to have a heart attack compared to individuals who are not depressed. This process has been poorly understood — until now. A new study led by Concordia University has found that depressed individuals have a slower recovery time after exercise compared to those who are non-depressed.

Critically ill patients who recover from a potentially deadly syndrome known as acute lung injury frequently emerge with new, apparently long-lasting depressive symptoms and new physical impairments that make them unable to perform many daily tasks, Johns Hopkins research suggests. Results of the new study, published in the American Journal of Respiratory and Critical Care Medicine, also suggest that the depressive symptoms frequently precede the new physical impairments, not the other way around.

Psychological interventions to prevent depression in children and adolescents can be useful and with protective effects that last for up to a year, finds a new systematic review. According to research cited in the new review, in 2002, depression ranked second greatest cause of disability in developed countries and first in many developing ones. The review appears in the current issue of The Cochrane Library, a publication of The Cochrane Collaboration, an international organization that evaluates medical research.

Experiencing a psychiatric episode within the first 30 days post-partum appears to be associated with an increased risk of developing bipolar affective disorder, according to a report published Online First by Archives of General Psychiatry, one of the JAMA/Archives journals. The study was carried out by Trine Munk-Olsen, Ph.D., of the National Centre for Register-Based Research, Arhus University, Arhus, Denmark, and colleagues.

Over a 10-year period, spending for Medicaid-enrolled patients with depression increased substantially but only minimal improvements in quality of care were observed, according to a report in the December issue of Archives of General Psychiatry, one of the JAMA/Archives journals. The study was carried out by Catherine A. Fullerton, M.D., M.P.H., of Harvard Medical School and Cambridge Health Alliance, Boston, and colleagues.

This study suggests an innovative psychological treatment called ‘concreteness training’ can reduce depression in just two months and could work as a self-help therapy for depression in primary care. Led by the University of Exeter and funded by the Medical Research Council, the research shows how this new treatment could help some of the 3.5 million people in the UK living with depression.

The negative effects of depression in young people on the health of their hearts may be stronger than previously recognized. Depression or a history of suicide attempts in people younger than 40, especially young women, markedly increases their risk for dying from heart disease, results from a nationwide study have revealed. The results are published in the November 2011 issue of Archives of General Psychiatry.

A new psychosocial approach shows promise in helping preschoolers with symptoms of depression function better and learn to regulate their emotions, according to an NIMH-funded study published online ahead of print October 31, 2011, in the Journal of Child Psychology and Psychiatry. Background Recent studies have shown that symptoms of clinical depression can arise in [...]

Results from the first multi-center pilot study of deep brain stimulation (DBS) for major depressive disorder were published online today by the Journal of Neurosurgery. The study, conducted at three research facilities in Canada, was designed to replicate and build upon an earlier study by Dr. Andres Lozano and Dr. Helen Mayberg which was published in the journal Neuron in 2005. Sponsored by St. Jude Medical, Inc. (NYSE:STJ), the study demonstrates significant improvement in depression symptoms among patients who are highly treatment resistant.

Patients with major depression who fail to see improvement after taking an antidepressant often have their initial medication switched or combined with a second drug. Many clinicians weigh the possibility of adverse side effects when deciding between strategies. New research in the latest issue of General Hospital Psychiatry now suggests one strategy may not be any more likely to be harmful than the other.