The use of aspirin at least once per month is associated with a significant decrease in pancreatic cancer risk, according to results of a large case-control study presented at the AACR 102nd Annual Meeting 2011. Xiang-Lin Tan, Ph.D., M.D., a research fellow at Mayo Clinic in Rochester, Minn., said the findings from this large collaborative study are preliminary and do not encourage widespread use of aspirin for this purpose.
Nicotine at doses similar to those found in most nicotine replacements therapies did not increase lung cancer tumor incidence, frequency or size, according to results of a mouse study presented at the AACR 102nd Annual Meeting 2011 by Phillip A. Dennis, M.D., Ph.D. Dennis is a senior investigator at the medical oncology branch of the National Cancer Institute.
Results of the NIH-AARP Diet and Health Study revealed that diabetes is associated with lower risk of prostate cancer in men but with higher risk of other cancers in both men and women. The data, to be presented at the AACR 102nd Annual Meeting 2011, held April 2-6, also showed an association between diabetes and higher cancer mortality rates.
Scientists have confirmed that metabolic syndrome, a constellation of conditions that increases the risk of heart disease and diabetes, may also increase the risk of the two most common types of liver cancer, according to data presented at the AACR 102nd Annual Meeting 2011, held April 2-6. The research is lead by Katherine McGlynn, Ph.D., a senior investigator at the National Cancer Institute.
In the largest study of its kind, researchers from a consortium of 44 universities and research institutions in the United States, including Rush University Medical Center, identified four new genes linked to Alzheimer’s disease. Each gene individually adds to the risk of having this common form of dementia later in life.
To parents, learning that a child has been diagnosed with autism can be overwhelming. Children with the disorder can seem trapped in a world of their own without friends or even a conception of friendship. Many prefer to play alone. Some lose the ability to speak more than a few words. But researchers at UNC are making progress in developing new techniques to detect and treat the disorder, said Geraldine Dawson, PhD, a professor of psychiatry at UNC and chief science officer for Autism Speaks, a research and advocacy organization.
In the single largest cancer genomics investigation reported to date, scientists have sequenced the whole genomes of tumors from 50 breast cancer patients and compared them to the matched DNA of the same patients’ healthy cells. This comparison allowed researchers to find mutations that only occurred in the cancer cells. They uncovered incredible complexity in the cancer genomes, but also got a glimpse of new routes toward personalized medicine.
A low dose of insulin has been found to suppress the expression in the blood of four precursor proteins involved in the pathogenesis of Alzheimer’s disease, according to new clinical research by University at Buffalo endocrinologists. The research, published in March online in the Journal of Clinical Endocrinology and Metabolism, suggests that insulin could have a powerful, new role to play in fighting Alzheimer’s disease.