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Adolescents diagnosed with schizophrenia and other psychoses appear to show greater decreases in gray matter volume and increases in cerebrospinal fluid in the frontal lobe compared to healthy adolescents without a diagnosis of psychosis, according to a report in the January issue of Archives of General Psychiatry, one of the JAMA/Archives journals. The research was carried out by Celso Arango, M.D., Ph.D., of the Hospital General Universitario Gregorio Marañón, Madrid, Spain, and colleagues.

Different ingredients in marijuana appear to affect regions of the brain differently during brain processing functions involving responses to certain visual stimuli and tasks, according to a report in the January issue of Archives of General Psychiatry, one of the JAMA/Archives journals. Sagnik Bhattacharyya, M.B.B.S., M.D., Ph.D, at the Institute of Psychiatry, King’s College in London, and colleagues studied 15 healthy men, who were occasional marijuana users, to examine the effects of Δ9-tetrahydrocannabinol (Δ9-THC) and cannabidiol (CBD) on regional brain function during salience processing, which is how people perceive things around them.

Children exposed to family violence show the same pattern of activity in their brains as soldiers exposed to combat, new research has shown. In the first functional MRI brain scan study to investigate the impact of physical abuse and domestic violence on children, scientists at UCL in collaboration with the Anna Freud Centre, found that exposure to family violence was associated with increased brain activity in two specific brain areas (the anterior insula and the amygdala) when children viewed pictures of angry faces.

New research suggests that, in people who do not currently have memory problems, those with smaller regions of the brain’s cortex may be more likely to develop symptoms consistent with very early Alzheimer’s disease. The study is published in the December 21, 2011, online issue of Neurology, the medical journal of the American Academy of Neurology.

Neuroscience researchers from Tufts have demonstrated, for the first time, that the physiological response to stress depends on neurosteroids acting on specific receptors in the brain, and they have been able to block that response in mice. This breakthrough suggests that these critical receptors may be drug therapy targets for control of the stress-response pathway. This finding may pave the way for new approaches to manage a wide range of neurological disorders involving stress.

Patients with Parkinson disease-related dementia appear to have increased brain atrophy in the hippocampal, temporal and parietal lobes and decreased prefrontal cortex volume compared to patients with Parkinson disease without dementia, according to a report in the December issue of Archives of Neurology, one of the JAMA/Archivesjournals. The study was conducted by Daniel Weintraub, M.D., of the Perelman School of Medicine, University of Pennsylvania, Philadelphia, and colleagues.

Swarms of bees and brain neurons make decisions using strikingly similar mechanisms, reports a new study in the Dec. 9 issue of Science. In previous work, Cornell University biologist Thomas Seeley clarified how scout bees in a honeybee swarm perform “waggle dances” to prompt other scout bees to inspect a promising site that has been found.

od maltreatment is associated with reductions in cerebral gray matter volume, and even if adolescents reporting exposure to maltreatment do not have symptoms that meet full criteria for psychiatric disorders, they may have cerebral gray matter changes that place them at risk for behavioral difficulties, according to a report in the December issue of Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals.

Epilepsy is common in children with autism spectrum disorders (ASD). A new study indicates their epilepsy is surprisingly photosensitive as well. Since photosensitive epilepsies can be triggered by flickering lights, the self-stimulatory behavior of ASD children, such as hand flapping in front of the face, has the potential to dramatically increase the risk of inducing photosensitive seizures.

Certain visual patterns and flashing images can provoke seizures in susceptible individuals, particularly among children and adolescents. Some media reports on the recent introduction of 3D-television sets suggest that this new technology may cause seizures in some viewers. Children who have epilepsy are somewhat more vulnerable to the provocative stimuli than their peers. But there has been no systematic examination of the potential effects 3D-TV may have on patients with epilepsy.