Drugs Encased In Nanoparticles Travel To Tumors On The Surface Of Immune-System Cells

On August 31, 2010, in Immunology, Meditation, by Christopher Fisher, PhD
drug carrying pouches on cells

Clinical trials using patients’ own immune cells to target tumors have yielded promising results. However, this approach usually works only if the patients also receive large doses of drugs designed to help immune cells multiply rapidly, and those drugs have life-threatening side effects. Now a team of MIT engineers has devised a way to deliver the necessary drugs by smuggling them on the backs of the cells sent in to fight the tumor.

Potential HIV Drug Keeps Virus Out Of Cells

On August 21, 2010, in Immunology, Medication, by Christopher Fisher, PhD
Illustration of the HIV-virus

Following up a pioneering 2007 proof-of-concept study, a University of Utah biochemist and colleagues have developed a promising new anti-HIV drug candidate, PIE12-trimer, that prevents HIV from attacking human cells. Michael S. Kay, M.D., Ph.D., associate professor of biochemistry in the University of Utah School of Medicine and senior author of the study published Wednesday, Aug. 18, 2010, online by the Journal of Virology, is raising funds to begin animal safety studies, followed by human clinical trials in two to three years.

Immune Function And Health Outcomes In Women With Depression

Natural Killer Cell

Researchers investigated immune function and health outcomes in women with depression, as compared with a non-depressed control group. Depression is a biological, psychological, and social illness that affects roughly 15 million American adults in any given year. Depression costs billions of dollars in lost time, productivity, personnel replacement, medical care and, tragically, loss of life. [...]

Flu’s Evolution Strategy Strikes Perfect Balance

On June 11, 2010, in Immunology, by Christopher Fisher, PhD
Flu Virus

Scientists have uncovered the flu’s secret formula for effectively evolving within and between host species: balance. The key lies with the flu’s unique replication process, which has evolved to produce enough mutations for the virus to spread and adapt to its host environment, but not so many that unwanted genomic mutations lead to the flu’s [...]

Cheese Found To Improve The Immune Response Of The Elderly

Cheese

Scientists in Finland have discovered that cheese can help preserve and enhance the immune system of the elderly by acting as a carrier for probiotic bacteria. The research, published in FEMS Immunology & Medical Microbiology, reveals that daily consumption of probiotic cheese helps to tackle age-related changes in the immune system.

Merely Seeing Disease Symptoms May Promote Aggressive Immune Response

On May 5, 2010, in Cognition, Immunology, by Christopher Fisher, PhD
Immune Reponse

Just seeing someone who looks sick is enough to make your immune system work harder, according to a new study in which volunteers looked at pictures of sick people. This may help fight off pathogens, says Mark Schaller from the University of British Columbia who conducted the research. “It seems like it’s probably good for [...]

Investigational Immune Intervention Slows Brain Shrinkage In Alzheimer’s Patients

Brain Map

An investigational intervention using naturally occurring antibodies in human blood has preserved the thinking abilities of a group of mild- to moderate-stage Alzheimer’s patients over 18 months and significantly reduced the rate of atrophy (shrinkage) of their brains, according to a study performed at the New York-Presbyterian Hospital/Weill Cornell Medical Center.

Secondhand Smoke Linked To Common Nasal And Sinus Condition

On April 24, 2010, in Immunology, Public Health, by Christopher Fisher, PhD

Nearly 40 percent of chronic rhinosinusitis diagnoses are linked to secondhand smoke, according to a Henry Ford Health System study. Researchers found that people are at increased risk for developing rhinosinusitis from exposure to secondhand smoke at home and public places like bars and restaurants, but that the risk is even higher at work and [...]

Stress During Pregnancy May Increase Offspring’s Risk of Developing Asthma

On April 22, 2010, in Anxiety, Immunology, by Christopher Fisher, PhD
Pregnant Women

During pregnancy, stress can have detrimental effects on both mother and child. Researchers at Brigham and Women’s Hospital (BWH) and Harvard Medical School have now found that stress during pregnancy may raise the risk of asthma in offspring. This study is published online in the American Journal of Respiratory and Critical Care Medicine on March [...]

The Impact Of Infections And Stress On Children With Tourette Syndrome And OCD

On April 12, 2010, in Immunology, by Christopher Fisher, PhD
Virus

PANDAS is an abbreviation for Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infections. This diagnosis was created when clinicians observed that following streptococcal infections, which include strep throat, scarlet fever, and impetigo, children developed tics and symptoms of obsessive-compulsive disorder (OCD).

Optimism Can Boost Your Immune System

On March 25, 2010, in Immunology, by Christopher Fisher, PhD
Happy Skier

Feeling better about the future might help you feel better for real. In a new study, psychological scientists Suzanne Segerstrom of the University of Kentucky and Sandra Sephton of the University of Louisville studied how law students’ expectations about the future affected their immune response. Their conclusions: Optimism may be good for your health.

Mother’s Flu During Pregnancy May Increase Her Baby’s Risk Of Schizophrenia

Infant

Roulette Smith, Ph.D. has long advocated the role of viruses in many different disorders (see: A Novel and Potentially Groundbreaking Viral Theory of Autism and Schizophrenia), including schizophrenia and Autism. Now researchers at University of Wisconsin-Madison in collaboration with the University of North Carolina at Chapel Hill report that Rhesus monkey babies born to mothers [...]

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