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Depression is actually defined by specific clinical symptoms such as sadness, difficulty to experience pleasure, and sleep problems that are present for at least two weeks with impairment of psychosocial functioning. These symptoms guide the physician to make a diagnosis and to select antidepressant treatment such as drugs or psychotherapy.

While some teenagers may puff on cigarettes to ‘self-medicate’ against the blues, scientists at the University of Toronto and the University of Montreal have found that smoking may actually increase depressive symptoms in some adolescents. Published in the journal Addictive Behaviors, the findings are part of the long-term Nicotine Dependence in Teens (NDIT) study based at the University of Montreal Hospital Research Centre.

A new study shows that having depression may nearly double your risk of developing dementia later in life. The research will be published in the July 6, 2010, issue of Neurology®, the medical journal of the American Academy of Neurology. Researchers examined data on 949 people with an average age of 79 from the Framingham Heart Study.

A new study at the University of Alabama at Birmingham (UAB) confirms the relationship between depression and abdominal obesity, which has been linked to an increased risk for cancer and cardiovascular disease. Included in this post is a video interview with Dr. Needham who discusses her current research.

An early response to second-course treatment is associated with greater likelihood of remission among teens with hard-to-treat depression, according to recent data from an NIMH-funded study published online ahead of print May 17, 2010, in the American Journal of Psychiatry. “These results suggest that early treatment decisions are probably the most crucial to the recovery [...]

Because people with depression often do not recognize they have a problem or are unable to describe their distress, many do not seek treatment. About a quarter of those with major depression are undiagnosed, according to several studies, and fewer than half receive treatment. To improve recognition and treatment of depression, primary care physicians should [...]

Patients with chronic kidney disease who have been diagnosed with depression are twice as likely to be hospitalized, progress to long-term dialysis treatments or die within a year as those who are not depressed, UT Southwestern Medical Center researchers have found. The study appears in the May 19 issue of the Journal of the American [...]

It is difficult to imagine a depressed third-grader. It is even more difficult to imagine a depressed preschooler. Although childhood depression is a well-recognized and treated disorder, only recently have research studies begun looking at depression in children younger than six years old. In the new Current Directions in Psychological Science, a journal of the [...]

A unique program for patients with depression has resulted in two and a half years without a single suicide from Henry Ford’s patient population. The program, chronicled in an article in this week’s issue of the Journal of the American Medical Association, was created by the Behavioral Health Services division of Henry Ford Health System [...]

A class of antidepressants known as selective serotonin reuptake inhibitors (SSRIs) may provide a boost to cardiovascular health by affecting the way platelets, small cells in the blood involved in clotting, clump together, say researchers at the Loyola University Medical Center in Maywood, Ill. In a study of 50 adults, the researchers found that platelets [...]

Treating clinical depression on the telephone is nearly as effective as face-to-face consultations, a new Brigham Young University study finds. The trial run included 30 people newly diagnosed with major depression. Instead of eight scheduled visits to the clinic, the participants covered the same material during a series of phone calls with the therapist. Calls [...]

Confirming results from earlier research, a clinical trial of treatment for major depression showed that the medication scopolamine, commonly used for motion sickness and as a sedative, could lift symptoms of depression within days, far faster than current antidepressants. Though the study was small, the magnitude of scopolamine’s effects in comparison with placebo suggests that [...]
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